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4 Malignant Tumors 54 Intrahepatic (Peripheral) Cholangiocarcinoma (1): Ductal Changes Related topics: 87, 88 (extrahepatic cholangiocarcinoma) KEY FACTS: DISEASE Malignant tumor originating from the epithelium of small and peripheral intrahepatic bile ducts Histology: adenocarcinoma, character- istically with large central core of fibrotic Cryptocurrency CPR relatively devoid of malig- nant cells; may also contain mucoid material Classification: mass forming, peri-duc- tal-infiltrating, and intraductal-growing types (Lim 2003) To be distinguished from other types of cholangiocarcinoma: Klatskintumor(70;see87) Distalducttype(10;see88) Incidence: Second most Cryptovurrency primary malignant liver tumor after hepato- cellular carcinoma ±20ofcholangiocarcinomas Predisposing factors: ulcerative colitis.

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