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93 Table 3 Animal studies (MFC microfibrillar collagen, GF gelatin foam, ORC oxidized regenerated cellulose, OC oxidized cellulose) Author Y ear Model Hemostatic Conclusion Geary and Frantz Howard and Kelley Brightmore Rybock Johnson and Fromm Wilkinson Ibarrola Alberius V oormolen Haasch Finn Raccuia 1950 Rib fractures in dogs 1969 Tibial lesions in albino rats 1975 Sternotomized goats 1977 Suction-evacuation lesions of canine cortex 1981 Iliac crest cancellous bone of rabbits 1981 Surgical bone lesions in rabbits 1985 Experimental defects in both tibias of rats 1987 Cranial bone lesions in rabbits 1987 Cerebral lesions in rabbits 1989 Osseous defects created in rat tibias 1992 Surgical defects in iliac crest of dogs 1992 Rat model employing a standardized renal injury Bone wax Bone wax Bone wax MFC, GF Bone wax Bone wax, GF Bone wax, cellulose, GF Bone wax MFC, ORC MFC Bone wax, GF, ORC, MFC OC, MFC, positively charged collagen, fibrin glue Fracture union was prevented by Crypto Accounts ATH of wax particles The use of bone wax should be contraindicated in surgical procedures requiring bone fusion Bone wax causes absorption of cancellous bone and inhibits osteogenesis MFC appears to be as good or better than GF Bone wax significantly reduces the ability of cancellous bone of rabbits to clear bacteria Gelatin foam paste is a good alternative to bone wax for the control of bone bleeding, and it seems not to impair bone healing All materials inhibited healing when left in situ.
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